Zhejiang U | College of Pharmaceutical Sciences | 中文版
     
     
Feng ZHU - IDRC - Chongqing University
ABOUT THE PRINCIPAL INVESTIGATOR

Dr. Feng ZHU

Distinguished Professor, Tenured Professor, Zhejiang University, China

Highly Cited Researcher, Clarivate, United States 

Web of Science  h-index: 60 ;    Scopus  h-index: 59 ;    Google  Scholar   h-index: 63

zhufeng(at)zju.edu.cn (primary), prof.zhufeng(at)gmail.com ; +86-571-88208444

PERSONAL DETAILS
Research Interests: Medicinal Chemistry, Drug Design, Target Discovery, Bioinformatics and System Biology

Based on the artificial intelligence and OMIC (proteomics and metabolomics) technologies, we conduct systematical exploration on the druggability and system profile of therapeutic drug targets, develop novel methods and online tools for target discovery, and further study the mechanism underlying the interaction between drugs and their corresponding targets.

  Academic Appointments and Educational Qualifications
  Honors and Awards
    Representative Honors & Awards

  • Leading Talent of the National High-Level Talent Special Support Plan of China (2020)
  • Honorable Professor of the Youth International Recruitment Program of China (2014)
  • Laureate of the Highly Cited Researcher of Clarivate (2023)
  • Leading Talent of the Science & Technology Nova Program of Chinese MOST (2019)
  • Corresponding Author of the Publications of Top-100 World-wide Impact of Chinese MOST (2021)
  • Laureate of the Fund for Distinguished Young Scholars of Zhejiang Province (2021)
  • Honorable Professor of the High-level Talent Support Plan of Zhejiang Province (2018)
  • Laureate of the Grand Prize in Natural Science of Bioinformatics Society of Zhejiang Province (Ranked the First,  2023)
  • Laureate of the 100,000 Top-scientists of Global Author ID Database (from 2021 to 2023)
  • Laureate of the 100,000 Top-scientists of Stanford University Science-wide Author Database (from 2021 to 2023)
  • Laureate of the Best Biology and Biochemistry Scientists of Global Academic Sites Research.com (from 2022 to 2023)
  • Laureate of the Top-10 Annual Scientific Advances in Bioinformatics in China of Elsevier Publication Group (2023)
  • Laureate of the 13th Top 10 Outstanding Students of Zhejiang University (Fengcheng Li, 2024)
  • Other Honors & Awards

  • Key Innovative Team Member of the Science & Technology Nova Program of Chinese MOST (2019)
  • Laureate of the First Class Science & Technology Award of Chongqing Province (Ranked the Fourth,  2019)
  • Laureate of the Leading Scholar in Social Practice of JiuSan Society (2021)
  • Supervisor of the Outstanding Doctor Postgraduate of Zhejiang Province (Fengcheng Li, 2023)
  • Supervisor of the Outstanding Doctor Postgraduate of Zhejiang Province (Jianbo Fu, 2021)
  • Supervisor of the Outstanding Master Postgraduate of Zhejiang Province (Jiajun Hong, 2020)
  • Laureate of the Excellent Teaching Case for Postgraduates of Zhejiang Province (2024)
  • Laureate of the Excellent Practical Achievement for Postgraduates of Zhejiang Province (2024)
  • Supervisor of the Third Class Challenge Cup Award of Zhejiang Province (2021)
  • Laureate of the Top Cited Paper Award of Wiley Publication Group (2020)
  • Laureate of the First Class Shihuayu Teaching Scholarship of Zhejiang University (2021)
  • Laureate of the School-level Teaching Scholarship (2023)
  • Supervisor of the Jiangzhi Biomedical Award of Zhejiang University (2020)
  • Supervisor of the Second Class Challenge Cup Award of Zhejiang University (2021)
  • Laureate of the Third Class Tanglixin Teaching Scholarship of Chongqing University (2014)
  • Laureate of the Top-10 Annual Scientific Advances of College of Pharmaceutical Sciences in Zhejiang University (2022,  2023)
  • Laureate of the Annual Outstanding Professor of College of Pharmaceutical Sciences in Zhejiang University (2020)
  • Laureate of the Annual Outstanding Professor of College of Pharmaceutical Sciences in Zhejiang University (2019)
  Educational Reform Projects (PI: Principal Investigator; PP: Project Participant)
  • 2022.10 - (PI, 省部级): IECC Foundation of the Ministry of Education of China (2022-AliC-4-32)
  • 2021.12 - (PI, 省部级): Textbook Construction in 13th Five-Year Plan of Zhejiang Province (2021-135-33)
  • 2021.01 - (PI, 学校级): Postgraduate Education Reform Foundation of China (zyjyjx-grazju-49)
  • 2020.06 - (PI, 学校级): Undergraduate Education Reform Foundation of China (068-484607)
  • 2020.09 - (PI, 学校级): Postgraduate Education Reform Foundation of Zhejiang University (1913039)
  Research Grants (PI: Principal Investigator; PP: Project Participant)
    Project(s) on Going

  • 2024.01 - (PI, 国家级): National Natural Science Foundation General Program of China (82373790)
  • 2023.01 - (PI, 国家级): National Natural Science Foundation Key Program of China (22220102001)
  • 2021.01 - (PI, 省部级): Fund for Distinguished Young Scholars of Zhejiang Province (LR21H300001)
  • 2020.10 - (PI, 国家级): National Leading Talent Special Support Plan of China (CWR-L-ZJU2020-ZF)
  • 2020.01 - (PI, 国家级): National Natural Science Foundation Collaboration Program of China (U1909208)
  • Project(s) Completed

  • 2014.06 - (PI, 国家级): Youth International Recruitment Program of China (IRPC-Y-CQU2014-ZF)
  • 2016.08 - (PI, 国家级): National Key Research and Development Program of China (2016YFC0902200)
  • 2018.09 - (PI, 国家级): National Key Research and Development Program of China (2018YFC0910500)
  • 2019.01 - (PI, 国家级): National Natural Science Foundation General Program of China (81872798)
  • 2013.01 - (PI, 国家级): National Natural Science Foundation Youth Program of China (81202459)
  • 2015.12 - (PI, 省部级): Special Fund for Chemical Drug Discovery of Chongqing Province (cstc2015zdcy-ztzx120003)
  • 2020.01 - (PI, 省部级): Key Research and Development Program of Zhejiang Province (2020C03010)
  • 2021.05 - (PI, 省部级): Research Fund for Injury Prevention of Zhejiang Province (181201*194232101)
  • 2012.09 - (PI, 省部级): Natural Science Foundation General Program of Chongqing Province (cstc2012jjA10116)
  • 2021.02 - (PI, 学校级): Fund for Future Digital Healthcare of Alibaba-ZJU Collaboration (ALIZJU202101)
  • 2017.07 - (PI, 学校级): Hundreds-Talents Program of Zhejiang University (ZJU2017070, evaluated as "Excellent")
  • 2012.07 - (PI, 学校级): Hundreds-Talents Program of Chongqing University (0903005203176, evaluated as "Excellent")
  • 2014.06 - (PI, 学校级): Major Fundation for Chongqing University (CDJZR14 46 88 01, evaluated as "Excellent")
  • 2013.01 - (PI, 学校级): Key Fundation for Chongqing University (CQDXWL-2012-Z003, evaluated as "Excellent")
  • 2018.01 - (PI, 学校级): Youth Research Innovation Grant of Zhejiang University (2018QNA7023)
  Published Key Textbooks ( front cover of the book)
  • 2023.01 (Undergraduate Textbook) : "AI in Medicine"     ISBN 978-7-308-23491-7, Zhejiang University Press
  • The Unique Feature of This Book:
    • Key Textbook for the Universities of Zhejiang Province in the 14th Five-Year Plan

  • 2023.06 (Drug Discovery Book) : "Artificial Intelligence and Drug Design"     ISBN 978-7-122-42928-5, Chemical Industry Press
  • The Unique Feature of This Book:
    • Key Project Supported by Chinese National Publication Foundation (2023)

  • 2023.03 (Undergraduate Textbook) : "Drug Design"     ISBN 978-7-04-059211-5, Higher Education Press
  • The Unique Feature of This Book:
    • Key Textbook for the Ministry of Industry and Information Technology of China
    • Key Textbook for the Medical Education of China in the 14th Five-Year Plan
    • Key Textbook for the National Education of China in the 11th Five-Year Plan

  Selected Core Publications (*corresponding author; published cover article; PDF version of paper)
  1. J. B. Fu, Y. Zhang, Y. X. Wang, H. N. Zhang, J. Liu, J. Tang, Q. X. Yang, H. C. Sun, W. Q. Qiu, Y. H. Ma, Z. R. Li, M. Y. Zheng, F. Zhu*. Optimization of metabolomic data processing using NOREVA. Nature Protocols (impact factor of the publication year: 17.0, 生物一区 TOP 期刊). 17(1): 129-151 (2022). PMID: 34952956.
  2. Featured Article: ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.26% in 2023.
    Media Coverage & News Report:

  3. L. Y. Zheng, S. Y. Shi, M. K. Lu, P. Fang, Z. Q. Pan, H. N. Zhang, Z. M. Zhou, H. Y. Zhang, M. J. Mou, S. J. Huang, L. Tao, W. Q. Xia, H. L. Li, Z. Y. Zeng, S. Zhang, Y. Z. Chen, Z. R. Li*, F. Zhu*. AnnoPRO: a strategy for protein function annotation based on multi-scale protein representation and a hybrid deep learning of dual-path encoding. Genome Biology (impact factor of the publication year: 12.3, 生物一区 TOP 期刊). 25(1):41 (2024). PMID: 38303023.
  4. Y. X. Wang, Z. Q. Pan, M. J. Mou, W. Q. Xia, H. N. Zhang, H. Y. Zhang, J. Liu, L. Y. Zheng, Y. C. Luo, H. Q. Zheng, X. Y. Yu, X. C. Lian, Z. Y. Zeng, Z. R. Li, B. Zhang, M. Y. Zheng, H. L. Li, T. J. Hou, F. Zhu*. A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder. Nucleic Acids Research (impact factor of the publication year: 19.2, 生物二区 TOP 期刊). 51(21): e110 (2023). PMID: 37889083.
  5. Y. X. Wang, S. Zhang, F. C. Li, Y. Zhou, Y. Zhang, Z. W. Wang, R. Y. Zhang, J. Zhu, Y. X. Ren, Y. Tan, C. Qin, Y. H. Li, X. X. Li, Y. Z. Chen*, F. Zhu*. Therapeutic target database 2020: enriched resource for facilitating research and early development of targeted therapeutics. Nucleic Acids Research (impact factor of the publication year: 16.9, 生物一区 TOP 期刊). 48(D1): 1031-1041 (2020). PMID: 31691823.
  6. Publication of World-wide Reputation : ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.12% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 0.13% in 2022.
    • The Percentile in Subject Area shown in InCites™ was 0.15% in 2021.
    Media Coverage & News Report:

  7. M. J. Mou, Z. Q. Pan, Z. M. Zhou, L. Y. Zheng, H. Y. Zhang, S. Y. Shi, F. C. Li, X. N. Sun, F. Zhu*. A transformer-based ensemble framework for the prediction of protein-protein interaction sites. Research (impact factor of the publication year: 11.0, 综合一区 TOP 期刊). 6: 0240 (2023). PMID: 37771850.
  8. Media Coverage & News Report:

  9. Q. X. Yang, B. Li, J. Tang, X. J. Cui, Y. X. Wang, X. F. Li, J. Hu, Y. Z. Chen, W. W. Xue, Y. Lou, Y. Q. Qiu*, F. Zhu*. Consistent gene signature of schizophrenia identified by a novel feature selection strategy from comprehensive sets of transcriptomic data. Briefings in Bioinformatics (impact factor of the publication year: 11.6, 生物一区 TOP 期刊). 21(3): 1058-1068 (2020). PMID: 31157371.
  10. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.29% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 0.56% in 2022.
    • The Percentile in Subject Area shown in InCites™ was 0.19% in 2021.

  11. Y. T. Zhang, Y. Zhou, Y. Zhou, X. Y. Yu, X. Y. Shen, Y. F. Hong, Y. X. Zhang, S. S. Wang, M. J. Mou, J. S. Zhang, L. Tao, J. Q. Gao, Y. Q. Qiu*, Y. Z. Chen*, F. Zhu*. TheMarker: a comprehensive database of therapeutic biomarkers. Nucleic Acids Research (impact factor of the publication year: 14.9, 生物二区 TOP 期刊). 52(D1): 1450-1464 (2024). PMID: 37850638.
  12. Cover Article:

  13. Y. Zhang, H. C. Sun, X. C. Lian, J. Tang, F. Zhu*. ANPELA: significantly enhanced quantification tool for cytometry-based single-cell proteomics. Advanced Science (impact factor of the publication year: 17.5, 工程技术一区 TOP 期刊). 10(15): e2207061 (2023). PMID: 36950745.
  14. Cover Article:

  15. Y. H. Li, X. X. Li, J. J. Hong, Y. X. Wang, J. B. Fu, H. Yang, C. Y. Yu, F. C. Li, J. Hu, W. W. Xue, Y. Y. Jiang, Y. Z. Chen*, F. Zhu*. Clinical trials, progression-speed differentiating features, and swiftness rule of the innovative targets of first-in-class drugs. Briefings in Bioinformatics (impact factor of the publication year: 11.6, 生物一区 TOP 期刊). 21(2): 649-662 (2020). PMID: 30689717.
  16. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.36% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 0.49% in 2022.
    • The Percentile in Subject Area shown in InCites™ was 0.09% in 2021.

  17. F. C. Li, J. Y. Yin, M. K. Lu, M. J. Mou, Z. R. Li, Z. Y. Zeng, Y. Tan, S. S. Wang, X. Y. Chu, H. B. Dai, T. J. Hou, S. Zeng*, Y. Z. Chen*, F. Zhu*. DrugMAP: molecular atlas and pharma-information of all drugs. Nucleic Acids Research (impact factor of the publication year: 19.2, 生物一区 TOP 期刊). 51(D1): 1288-1299 (2023). PMID: 36243961.
  18. Cover Article: Media Coverage & News Report:

  Selected Important Publications (*corresponding author; published cover article; PDF version of paper)
  1. Q. X. Yang, Y. X. Wang, Y. Zhang, F. C. Li, W. Q. Xia, Y. Zhou, Y. Q. Qiu, H. L. Li, F. Zhu*. NOREVA: enhanced normalization and evaluation of time-course and multi-class metabolomic data. Nucleic Acids Research (impact factor of the publication year: 16.9, 生物一区 TOP 期刊). 48(W1): 436-448 (2020). PMID: 32324219.
  2. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.87% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 1.60% in 2022.
    Media Coverage & News Report :

  3. X. N. Sun, Y. T. Zhang, H. Y. Li, Y. Zhou, S. Y. Shi, Z. Chen, X. He, H. Y. Zhang, F. C. Li, J. Y. Yin, M. J. Mou, Y. Z. Wang, Y. Q. Qiu, F. Zhu*. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Research (impact factor of the publication year: 19.2, 生物一区 TOP 期刊). 51(D1): 1263-1275 (2023). PMID: 36243960.
  4. Media Coverage & News Report:

  5. J. Y. Yin, F. C. Li, Y. Zhou, M. J. Mou, Y. J. Lu, K. L. Chen, J. Xue, Y. C. Luo, J. B. Fu, X. He, J. Q. Gao, S. Zeng*, L. S. Yu*, F. Zhu*. INTEDE: interactome of drug-metabolizing enzymes. Nucleic Acids Research (impact factor of the publication year: 19.2, 生物一区 TOP 期刊). 49(D1): 1233-1243 (2021). PMID: 33045737.
  6. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 1.01% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 1.12% in 2022.
    Media Coverage & News Report :

  7. B. Li, J. Tang, Q. X. Yang, S. Li, X. J. Cui, Y. H. Li, Y. Z. Chen, W. W. Xue, X. F. Li, F. Zhu*. NOREVA: normalization and evaluation of MS-based metabolomics data. Nucleic Acids Research (impact factor of the publication year: 10.2, 生物一区 TOP 期刊). 45(W1): 162-170 (2017). PMID: 28525573.
  8. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.60% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 0.77% in 2022.
    • The Percentile in Subject Area shown in InCites™ was 0.71% in 2021.
    • The Percentile in Subject Area shown in InCites™ was 0.75% in 2020.
    • The Percentile in Subject Area shown in InCites™ was 1.27% in 2019.
    • The Percentile in Subject Area shown in InCites™ was 2.98% in 2018.
    Highlights by Experts in Subject Area:
    • Introduced by OMICTOOLS as "provided valuable guidance to the selection of suitable algorithm in metabolomics".
    • Discussed in StackExchange as "works fine" and "corrections for batches without QC options".

  9. J. Y. Yin, W. Sun, F. C. Li, J. J. Hong, X. X. Li, Y. Zhou, Y. J. Lu, M. Z. Liu, X. Zhang, N. Chen, X. P. Jin, J. Xue, S. Zeng*, L. S. Yu*, F. Zhu*. VARIDT 1.0: variability of drug transporter database. Nucleic Acids Research (impact factor of the publication year: 16.9, 生物一区 TOP 期刊). 48(D1): 1042-1050 (2020). PMID: 31495872.
  10. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.81% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 0.96% in 2022.
    • The Percentile in Subject Area shown in InCites™ was 0.33% in 2021.
    Media Coverage & News Report :

  11. J. Tang, J. B. Fu, Y. X. Wang, B. Li, Y. H. Li, Q. X. Yang, X. J. Cui, J. J. Hong, X. F. Li, Y. Z. Chen, W. W. Xue, F. Zhu*. ANPELA: analysis and performance-assessment of the label-free quantification workflow for metaproteomic studies. Briefings in Bioinformatics (impact factor of the publication year: 11.6, 生物一区 TOP 期刊). 21(2): 621-636 (2020). PMID: 30649171.
  12. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.30% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 0.20% in 2022.
    • The Percentile in Subject Area shown in InCites™ was 0.05% in 2021.

  13. F. C. Li, Y. Zhou, Y. Zhang, J. Y. Yin, Y. Q. Qiu, J. Q. Gao, F. Zhu*. POSREG: proteomic signature discovered by simultaneously optimizing its reproducibility and generalizability. Briefings in Bioinformatics (impact factor of the publication year: 13.9, 生物一区 TOP 期刊). 23(2): bbac040 (2022). PMID: 35183059.
  14. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.06% in 2023.

  15. S. Zhang, K. Amahong, C. Y. Zhang, F. C. Li, J. Q. Gao, Y. Q. Qiu*, F. Zhu*. RNA-RNA interactions between SARS-CoV-2 and host benefit viral development and evolution during COVID-19 infection. Briefings in Bioinformatics (impact factor of the publication year: 13.9, 生物一区 TOP 期刊). 23(1): bbab397 (2022). PMID: 34585235.
  16. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.12% in 2023.

  17. J. J. Hong, Y. C. Luo, Y. Zhang, J. B. Ying, W. W. Xue, T. Xie, L. Tao*, F. Zhu*. Protein functional annotation of simultaneously improved stability, accuracy and false discovery rate achieved by a sequence-based deep learning. Briefings in Bioinformatics (impact factor of the publication year: 11.6, 生物一区 TOP 期刊). 21(4): 1437-1447 (2020). PMID: 31504150.
  18. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.58% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 0.94% in 2022.

  19. Q. X. Yang, Y. X. Wang, F. C. Li, S. Zhang, Y. C. Luo, Y. Li, J. Tang, B. Li, Y. Z. Chen, W. W. Xue, F. Zhu*. Identification of the gene signature reflecting schizophrenia's etiology by constructing artificial intelligence-based method of enhanced reproducibility. CNS Neuroscience & Therapeutics (impact factor of the publication year: 7.0, 医学一区 TOP 期刊). 25(9): 1054-1063 (2019). PMID: 31350824.
  20. Cover Article:

  21. Z. J. Han, W. W. Xue, L. Tao, F. Zhu*. Identification of novel immune-relevant drug target genes for alzheimer's disease by combining ontology inference with network analysis. CNS Neuroscience & Therapeutics (impact factor of the publication year: 7.0, 医学一区 TOP 期刊). 24(12): 1253-1263 (2018). PMID: 30106219.
  22. Honors and Awards:
    • Wiley Top Cited Paper Award (2020).
    Cover Article:

  23. J. Tang, J. B. Fu, Y. X. Wang, Y. C. Luo, Q. X. Yang, B. Li, G. Tu, J. J. Hong, X. J. Cui, Y. Z. Chen, L. X. Yao, W. W. Xue, F. Zhu*. Simultaneous improvement in the precision, accuracy and robustness of label-free proteome quantification by optimizing data manipulation chains. Molecular & Cellular Proteomics (impact factor of the publication year: 7.4, 生物一区 TOP 期刊). 18(8): 1683-1699 (2019). PMID: 31097671.
  24. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.87% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 1.12% in 2022.
    • The Percentile in Subject Area shown in InCites™ was 0.81% in 2021.
    • The Percentile in Subject Area shown in InCites™ was 0.57% in 2020.

  25. F. C. Li, Y. Zhou, X. Y. Zhang, J. Tang, Q. X. Yang, Y. Zhang, Y. C. Luo, J. Hu*, W. W. Xue, Y. Q. Qiu, Q. J. He, B. Yang, F. Zhu*. SSizer: determining the sample sufficiency for comparative biological study. Journal of Molecular Biology (impact factor of the publication year: 5.1, 生物二区 TOP 期刊). 432(11): 3411-3421 (2020). PMID: 32044343.
  26. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 2.93% in 2023.

  27. W. W. Xue, F. Y. Yang, P. P. Wang, G. X. Zheng, Y. Z. Chen, X. J. Yao, F. Zhu*. What contributes to serotonin-norepinephrine reuptake inhibitors' dual-targeting mechanism? The key role of transmembrane domain 6 in human serotonin and norepinephrine transporters revealed by molecular dynamics simulation. ACS Chemical Neuroscience (impact factor of the publication year: 4.2, 化学二区 TOP 期刊). 9(5): 1128-1140 (2018). PMID: 29300091.
  28. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.11% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 0.18% in 2022.
    • The Percentile in Subject Area shown in InCites™ was 0.14% in 2021.
    • The Percentile in Subject Area shown in InCites™ was 0.21% in 2020.
    • The Percentile in Subject Area shown in InCites™ was 0.29% in 2019.

  29. Y. Zhang, J. B. Ying, J. J. Hong, F. C. Li, T. T. Fu, F. Y. Yang, G. X. Zheng, X. J. Yao, Y. Lou, Y. Q. Qiu, W. W. Xue*, F. Zhu*. How does chirality determine the selective inhibition of histone deacetylase 6? A lesson from Trichostatin A enantiomers based on molecular dynamics. ACS Chemical Neuroscience (impact factor of the publication year: 4.2, 化学二区 TOP 期刊). 10(5): 2467-2480 (2019). PMID: 30784262.
  30. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.48% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 1.85% in 2022.
    • The Percentile in Subject Area shown in InCites™ was 1.19% in 2021.
    • The Percentile in Subject Area shown in InCites™ was 0.74% in 2020.
    Cover Article:

  31. W. W. Xue, T. T. Fu, S. Z. Deng, F. Y. Yang, J. Y. Yang, F. Zhu*. Molecular mechanism for the allosteric inhibition of the human serotonin transporter by antidepressant escitalopram. ACS Chemical Neuroscience (impact factor of the publication year: 5.8, 医学二区期刊). 13(3): 340-351 (2022). PMID: 35041375.
  32. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.05% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 0.09% in 2022.

  33. Q. X. Yang, B. Li, S. J. Chen, J. Tang, Y. H. Li, Y. Li, S. Zhang, C. Shi, Y. Zhang, M. J. Mou, W. W. Xue*, F. Zhu*. MMEASE: online meta-analysis of metabolomic data by enhanced metabolite annotation, marker selection and enrichment analysis. Journal of Proteomics (impact factor of the publication year: 4.0, 生物二区期刊). 232: 104023 (2021). PMID: 33130111.
  34. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.69% in 2023.
    • The Percentile in Subject Area shown in InCites™ was 2.51% in 2022.

  35. Y. X. Wang, Z. Chen, Z. Q. Pan, S. J. Huang, J. Liu, W. Q. Xia, H. N. Zhang, M. Y. Zheng, H. L. Li, T. J. Hou, F. Zhu*. RNAincoder: a deep learning-based encoder for RNA and RNA-associated interaction. Nucleic Acids Research (impact factor of the publication year: 19.2, 生物一区 TOP 期刊). 51(W1): 509-519 (2023). PMID: 37166951.
  36. Y. Zhou, Y. T. Zhang, D. H. Zhao, X. Y. Yu, X. Y. Shen, Y. Zhou, S. S. Wang, Y. Q. Qiu, Y. Z. Chen*, F. Zhu*. TTD: Therapeutic Target Database describing target druggability information. Nucleic Acids Research (impact factor of the publication year: 19.2, 生物二区 TOP 期刊). 52(D1): 1465-1477 (2024). PMID: 37713619.
  37. L. T. Shen, X. N. Sun, Z. Chen, Y. Guo, Z. Y. Shen, Y. Song, W. X. Xin, H. Y. Ding, X. Y. Ma, W. B. Xu, W. Y. Zhou, J. X. Che, L. L. Tan, L. S. Chen, S. Q. Chen, X. W. Dong*, L. Fang*, F. Zhu*. ADCdb: the database of antibody-drug conjugates. Nucleic Acids Research (impact factor of the publication year: 19.2, 生物二区 TOP 期刊). 52(D1): 1097-1109 (2024). PMID: 37831118.
  38. X. C. Lian, Y. T. Zhang, Y. Zhou, X. N. Sun, S. J. Huang, H. B. Dai*, L. Y. Han*, F. Zhu*. SingPro: a knowledge base providing single-cell proteomic data. Nucleic Acids Research (impact factor of the publication year: 19.2, 生物二区 TOP 期刊). 52(D1): 552-561 (2024). PMID: 37819028.
  39. M. K. Lu, J. Y. Yin, Q. Zhu, G. L. Lin, M. J. Mou, F. Y. Liu, Z. Q. Pan, N. X. You, X. C. Lian, F. C. Li, H. N. Zhang, L. Y. Zheng, W. Zhang, H. Y. Zhang, Z. H. Shen, Z. Gu, H. L. Li*, F. Zhu*. Artificial intelligence in pharmaceutical sciences. Engineering (impact factor of the publication year: 12.8, 工程技术一区 TOP 期刊). 27: 37-69 (2023). PMID: N.A.
  40. L. Y. Zheng, S. Y. Shi, X. N. Sun, M. K. Lu, Y. Liao, S. S. Zhu, H. N. Zhang, Z. Q. Pan, P. Fang, Z. Y. Zeng, H. L. Li, Z. R. Li*, W. W. Xue*, F. Zhu*. MoDAFold: a strategy for predicting the structure of missense mutant protein based on AlphaFold2 and molecular dynamics. Briefings in Bioinformatics (impact factor of the publication year: 9.5, 生物二区 TOP 期刊). 25(2): bbae006 (2024). PMID: 38305456.
  41. F. C. Li, J. Y. Yin, M. K. Lu, Q. X. Yang, Z. Y. Zeng, B. Zhang, Z. R. Li, Y. Q. Qiu, H. B. Dai, Y. Z. Chen*, F. Zhu*. ConSIG: consistent discovery of molecular signature from OMIC data. Briefings in Bioinformatics (impact factor of the publication year: 13.9, 生物一区 TOP 期刊). 23(4): bbac253 (2022). PMID: 35758241
  42. J. Y. Yin, H. Y. Zhang, X. N. Sun, N. X. You, M. J. Mou, M. K. Lu, Z. Q. Pan, F. C. Li, H. L. Li*, S. Zeng*, F. Zhu*. Decoding drug response with structurized gridding map-based cell representation. IEEE Journal of Biomedical and Health Informatics (impact factor of the publication year: 7.7, 工程技术一区 TOP 期刊). doi: 10.1109/JBHI.2023.3342280 (2024). PMID: 38090819.
  43. Q. X. Yang, S. M. Chen, W. Y. Jiang, L. Mi, J. R. Liu, Y. Hu, X. L. Ji*, J. Wang*, F. Zhu*. MultiClassMetabo: superior classification model constructed using metabolic markers in multiclass metabolomics. Analytical Chemistry (impact factor of the publication year: 7.4, 化学一区 TOP 期刊). 96(4):1410-1418 (2024). PMID: 38221713.
  44. J. Tang, M. J. Mou, X. Zheng, J. Yan, Z. Q. Pan, J. S. Zhang, B. Li, Q. X. Yang, Y. X. Wang, Y. Zhang, J. Q. Gao, S. Li*, H. Yang*, F. Zhu*. Strategy for identifying a robust metabolomic signature reveals the altered lipid metabolism in pituitary adenoma. Analytical Chemistry (impact factor of the publication year: 7.4, 化学一区 TOP 期刊). doi: 10.1021/acs.analchem.3c03796 (2024). PMID: 38417094.
  45. Y. X. Wang, F. C. Li, Y, Zhang, Y. Zhou, Y. Tan, Y. Z. Chen*, F. Zhu*. Databases for the targeted COVID-19 therapeutics. British Journal of Pharmacology (impact factor of the publication year: 7.7, 医学二区 TOP 期刊). 177(21): 4999-5001 (2020). PMID: 32845521.
  46. S. Zhang, K. Amahong, Y. T. Zhang, X. P. Hu, S. J. Huang, M. K. Lu, Z. Y. Zeng, Z. R. Li, B. Zhang, Y. Q. Qiu, H. B. Dai, J. Q. Gao, F. Zhu*. RNAenrich: a web server for non-coding RNA enrichment. Bioinformatics (impact factor of the publication year: 6.9, 生物二区 TOP 期刊). 39(7): btad421 (2023). PMID: 37399102.
  47. W. Zhang, M. J. Mou, W. Hu, M. K. Lu, H. Y. Zhang, H. N. Zhang, Y. C. Luo, H. Q. Xu, L. Tao, H. B. Dai, J. Q. Gao*, F. Zhu*. MOINER: a novel multi-omics early integration framework for biomedical classification and biomarker discovery. Journal of Chemical Information and Modeling (impact factor of the publication year: 5.6, 化学二区 TOP 期刊). doi: 10.1021/acs.jcim.4c00013 (2024). PMID: 38373720.
  48. T. T. Fu, G. Tu, M. Ping, G. X. Zheng, F. Y. Yang, J. Y. Yang, Y. Zhang, X. J. Yao, W. W. Xue*, F. Zhu*. Subtype selective mechanisms of negative allosteric modulators binding to group I metabotropic glutamate receptors. Acta Pharmacologica Sinica (impact factor of the publication year: 6.2, 医学一区 TOP 期刊). 42(8): 1354-1367 (2021). PMID: 33122823.
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Nature Biotechnol (IF = 46.9); Nature Mach Intell (IF = 23.8); Science Adv (IF = 13.6);
Cell Discov (IF = 33.5); Nucleic Acids Res (IF = 19.2); Med Res Rev (IF = 12.9);
Nature Protoc (IF = 17.0); Brief Bioinform (IF = 13.9); Br J Pharmacol (IF = 8.7);
Proc Natl Acad Sci U S A (IF = 12.8); Anal Chem (IF = 8.0); Bioinformatics (IF = 6.9);
J Med Chem (IF = 8.0); Pharmacol Res (IF = 10.3); J Chem Inf Model (IF = 6.2)


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